Is COVID-19 receiving ADE from other coronaviruses?
Identifieur interne : 000635 ( an2020/Analysis ); précédent : 000634; suivant : 000636Is COVID-19 receiving ADE from other coronaviruses?
Auteurs : Jason A. Tetro [Canada]Source :
- Microbes and infection [ 1769-714X ] ; 2020.
Descripteurs français
- KwdFr :
- MESH :
- anatomopathologie : Infections à coronavirus, Pneumopathie virale.
- mortalité : Infections à coronavirus, Pneumopathie virale.
- épidémiologie : Chine.
- Facilitation dépendante des anticorps, Géographie médicale, Humains, Pandémies.
- Wicri :
- geographic : République populaire de Chine.
English descriptors
- KwdEn :
- MESH :
- geographic , epidemiology : China.
- immunology : Betacoronavirus.
- mortality : Coronavirus Infections, Pneumonia, Viral.
- pathogenicity : Betacoronavirus.
- pathology : Coronavirus Infections, Pneumonia, Viral.
- Antibody-Dependent Enhancement, Geography, Medical, Humans, Pandemics.
Abstract
One of the most perplexing questions regarding the current COVID-19 coronavirus epidemic is the discrepancy between the severity of cases observed in the Hubei province of China and those occurring elsewhere in the world. One possible answer is antibody dependent enhancement (ADE) of SARS-CoV-2 due to prior exposure to other coronaviruses. ADE modulates the immune response and can elicit sustained inflammation, lymphopenia, and/or cytokine storm, one or all of which have been documented in severe cases and deaths. ADE also requires prior exposure to similar antigenic epitopes, presumably circulating in local viruses, making it a possible explanation for the observed geographic limitation of severe cases and deaths.
DOI: 10.1016/j.micinf.2020.02.006
PubMed: 32092539
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000A46
- to stream PubMed, to step Curation: 000A46
- to stream PubMed, to step Checkpoint: 000592
- to stream Ncbi, to step Merge: 000B18
- to stream Ncbi, to step Curation: 000B18
- to stream Ncbi, to step Checkpoint: 000B18
- to stream Main, to step Merge: 000637
- to stream Main, to step Curation: 000635
- to stream Main, to step Exploration: 000635
- to stream an2020, to step Extraction: 000635
Links to Exploration step
pubmed:32092539Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Is COVID-19 receiving ADE from other coronaviruses?</title><author><name sortKey="Tetro, Jason A" sort="Tetro, Jason A" uniqKey="Tetro J" first="Jason A" last="Tetro">Jason A. Tetro</name><affiliation wicri:level="1"><nlm:affiliation>College of Biological Sciences, University of Guelph, Guelph, Ontario, N1G 2W1, Canada. Electronic address: jason@jasontetro.com.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>College of Biological Sciences, University of Guelph, Guelph, Ontario, N1G 2W1</wicri:regionArea><wicri:noRegion>N1G 2W1</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32092539</idno><idno type="pmid">32092539</idno><idno type="doi">10.1016/j.micinf.2020.02.006</idno><idno type="wicri:Area/PubMed/Corpus">000A46</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000A46</idno><idno type="wicri:Area/PubMed/Curation">000A46</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000A46</idno><idno type="wicri:Area/PubMed/Checkpoint">000592</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000592</idno><idno type="wicri:Area/Ncbi/Merge">000B18</idno><idno type="wicri:Area/Ncbi/Curation">000B18</idno><idno type="wicri:Area/Ncbi/Checkpoint">000B18</idno><idno type="wicri:Area/Main/Merge">000637</idno><idno type="wicri:Area/Main/Curation">000635</idno><idno type="wicri:Area/Main/Exploration">000635</idno><idno type="wicri:Area/an2020/Extraction">000635</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Is COVID-19 receiving ADE from other coronaviruses?</title><author><name sortKey="Tetro, Jason A" sort="Tetro, Jason A" uniqKey="Tetro J" first="Jason A" last="Tetro">Jason A. Tetro</name><affiliation wicri:level="1"><nlm:affiliation>College of Biological Sciences, University of Guelph, Guelph, Ontario, N1G 2W1, Canada. Electronic address: jason@jasontetro.com.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>College of Biological Sciences, University of Guelph, Guelph, Ontario, N1G 2W1</wicri:regionArea><wicri:noRegion>N1G 2W1</wicri:noRegion></affiliation></author></analytic><series><title level="j">Microbes and infection</title><idno type="eISSN">1769-714X</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antibody-Dependent Enhancement</term><term>Betacoronavirus (immunology)</term><term>Betacoronavirus (pathogenicity)</term><term>China (epidemiology)</term><term>Coronavirus Infections (mortality)</term><term>Coronavirus Infections (pathology)</term><term>Geography, Medical</term><term>Humans</term><term>Pandemics</term><term>Pneumonia, Viral (mortality)</term><term>Pneumonia, Viral (pathology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Chine (épidémiologie)</term><term>Facilitation dépendante des anticorps</term><term>Géographie médicale</term><term>Humains</term><term>Infections à coronavirus (anatomopathologie)</term><term>Infections à coronavirus (mortalité)</term><term>Pandémies</term><term>Pneumopathie virale (anatomopathologie)</term><term>Pneumopathie virale (mortalité)</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>China</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Infections à coronavirus</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Betacoronavirus</term></keywords><keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Infections à coronavirus</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Betacoronavirus</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Chine</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Antibody-Dependent Enhancement</term><term>Geography, Medical</term><term>Humans</term><term>Pandemics</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Facilitation dépendante des anticorps</term><term>Géographie médicale</term><term>Humains</term><term>Pandémies</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>République populaire de Chine</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">One of the most perplexing questions regarding the current COVID-19 coronavirus epidemic is the discrepancy between the severity of cases observed in the Hubei province of China and those occurring elsewhere in the world. One possible answer is antibody dependent enhancement (ADE) of SARS-CoV-2 due to prior exposure to other coronaviruses. ADE modulates the immune response and can elicit sustained inflammation, lymphopenia, and/or cytokine storm, one or all of which have been documented in severe cases and deaths. ADE also requires prior exposure to similar antigenic epitopes, presumably circulating in local viruses, making it a possible explanation for the observed geographic limitation of severe cases and deaths.</div></front></TEI><affiliations><list><country><li>Canada</li></country></list><tree><country name="Canada"><noRegion><name sortKey="Tetro, Jason A" sort="Tetro, Jason A" uniqKey="Tetro J" first="Jason A" last="Tetro">Jason A. Tetro</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV2/Data/an2020/Analysis
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000635 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/an2020/Analysis/biblio.hfd -nk 000635 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= CovidV2
|flux= an2020
|étape= Analysis
|type= RBID
|clé= pubmed:32092539
|texte= Is COVID-19 receiving ADE from other coronaviruses?
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/an2020/Analysis/RBID.i -Sk "pubmed:32092539" \
| HfdSelect -Kh $EXPLOR_AREA/Data/an2020/Analysis/biblio.hfd \
| NlmPubMed2Wicri -a CovidV2
| This area was generated with Dilib version V0.6.33. |  |